Telescopes tend to be on mountains, far away from the lights of cities, spurious electronic signals, and above the bulk of dust and atmospheric water that can interfere with certain observations. They also tend to be in places with good weather, of course. This combines to put optical observatories in some very lovely places, i.e. scenic mountaintops that are sun-splashed in the day and capped by diamond skies at night.
Many observatories are very high and remote, and it can be a hassle getting there. But it is always worth the trip, even just from a sight-seeing point of view. Kitt Peak National Observatory is not so terribly high nor far from habitation, and the desert (if you like that sort of thing, which I do) is wonderful to drive through.
It is one of the perks of astronomy, just traveling to observatories. There is something thrilling in taking a turn on a winding mountain road and suddenly seeing the brilliant white dome of a telescope come into view. It feels magical to me - a place for looking deep into the darkness, and learning what's out there.